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  開發具轉移型腫瘤靶向性之近紅外光長餘輝奈米材料用於肺癌化療  
   
    Development of Metastatic Tumor-Targeting NIR Persistent Luminescence Nanomaterials to Chemotherapy for Lung Cancer  
   

 

肺癌高居全球癌症死因之冠,其死亡人數超過乳腺癌、結腸癌與前列腺癌之死亡總和。其中,非小細胞型肺癌(non-small cell lung cancer,NSCLC)為主要肺癌類型。因其有效治療手段有限,尤其是如何改善患者治癒後復發為目前癌症醫學一大挑戰。……。

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Lung cancer remains the leading cause of cancer-related deaths worldwide, surpassing the combined fatalities caused by breast, colon, and prostate tumors. Effective treatment options for non-small cell lung cancer (NSCLC) are limited, posing a significant challenge in improving patient outcomes. .…….

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  調控免疫突觸以促進伽瑪-德爾塔T細胞抗癌療效  
   
    Building a Stronger Bond Between Cancer and Fighter Immune Cells to Combat Cancer  
   

 

癌症免疫療法為許多晚期癌症病患提供新的治療契機,近年來新興的「免疫細胞治療」,運用病人自身的免疫細胞,經體外培養、擴增且活化後,再回輸病人體內對抗癌細胞,在臨床上逐漸得到重視,然而免疫細胞種類繁多,製程繁複且活性不一,仍有許多問題待克服。……。

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Cell-based immunotherapy, a type of therapy that takes immune cells from a patient, grows and expands these cells in the laboratory, and infuses the cells back into the patient, has shown some promise in the clinical setting. .…….

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  研究非典型染色體末端延長模式  
   
    Alternative Lengthening Of Telomeres  
   

 

台灣大學朱雪萍與中研院陳律佑研究團隊合作研究非典型染色體末端延長模式,發現參與在DNA 修復中的XPF蛋白,扮演了一個重要的角色,此項研究提供了對於治療癌症的新契機。……。

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The maintenance of telomere length is closely related to the processes of cancers and aging. How do telomeres extend their length? It has been well-known that an enzyme called telomerase can lengthen telomeres.……。

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