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| 組蛋白去乙醯化酶HDA15和MOS4複合物亞基 MAC3A/3B共同調節ABA響應基因的內含子保留 | ||||||
| HISTONE DEACETYLASE 15 and MOS4-Associated Complex subunits 3A/3B coregulate intron retention of ABA-responsive genes | ||||||
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國立臺灣大學吳克強研究團隊與中央研究院陳柏仰團隊合作研究植物在生長發育及逆境反應的表觀遺傳調控機制。臺灣大學吳克強研究團隊通過突變體分析，質譜分析，蛋白質體學及轉錄體研究，結合中研院陳柏仰研究團隊的生物資訊學分析，揭示了組蛋白去乙醯化酶HDA15參與阿拉伯芥脫落酸 (ABA) 反應的分子機制。……。 【閱讀全文】 |
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Dr. Keqiang Wu’s team of National Taiwan University collaborated with Dr. Pao-Yang Chen's team of Academia Sinica to study the epigenetic regulation mechanism of plant development and stress response. Through the mutant analysis, mass spectrometry analysis, proteomics and transcriptome studies carried out by the Wu’s team, combined with bioinformatics analysis by the Chen's team, the molecular mechanism how the histone deacetylase HDA15 is involved in the abscisic acid (ABA) response in Arabidopsis was revealed. .……. |
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| 結合機器學習模型和功能性微生物基因組策略來鑑別可降解六溴環十二烷的關鍵基因群 | ||||||
| Interpretation of Machine Learning-Based Prediction Models and Functional Metagenomic Approach to Identify Critical Genes in Hexabromocyclododecane Degradation | ||||||
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臺灣大學施養信與中研院林仲彥研究團隊合作研究透過微生物功能性解析和機器學習策略，來分析環境總體基因體資料，尋找參與六溴環十二烷（HBCD）降解的關鍵基因。HBCD是持久性有機污染物（POPs）中的一種，對環境造成嚴重風險。透過微生物降解處理 HBCD 污染是一個環境友善且有效的解決方案，但尋找有效的微生物和其對應基因一直是一個耗時且耗費資源的過程。……。 【閱讀全文】 |
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Hexabromocyclododecane (HBCD) is one of the persistent organic pollutants (POPs) and poses serious risks. Tackling HBCD contamination through microbial degradation is promising, but identifying the effective microbes and genes has been complex. A joint research team led by NTU Prof. Yang-Hsin Shih and Academia Sinica Prof. Chung-Yen Lin has made significant progress using metagenomics combined with machine learning to uncover key genes involved in HBCD breakdown. .……. |
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| 解析中國 ─ 歐亞世界複雜的政治與宗教互動 | ||||||
| Analyzing the Complex Interactions between the Politics and Religions in China and Eurasia | ||||||
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政治與宗教的互動，是人類歷史中普遍可見的現象，並持續對現當代社會造成深遠影響。傳統中國社會，宗教與政治亦息息相關，從佛教興盛前的祭祀與鬼神信仰，到佛教席捲中國後的深刻衝擊，以至於多元宗教和地域傳統的各種刺激，皆可見政教互動的存在之重。但相較於其重大的歷史意義，既有研究仍有許多可進一步開展的空間。本計畫由孔令偉（中研院史語所）和傅揚（臺大歷史系）主持，團隊成員包括甘懷真（臺大歷史系）、林智莉（臺大戲劇系）、徐兆安（中研院近史所）、廖肇亨（中研院文哲所），以十八世紀前的政治與宗教互動為主題，嘗試提出新的發現、拓展未來研究方向，並建立有活力的研究團隊。……。 【閱讀全文】 |
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In traditional China, religions and politics were closely intertwined. From the pre-Buddhist rituals and beliefs in ghosts and spirits, to the profound impact of Buddhism’s sweep through China, to the stimulation of multiple religions and regional traditions, the significance of the interaction between the politics and religions in China’s history is evident. However, compared to its historical significance, there is still much room for further research. Focusing on the relationship between the politics and religions before the eighteenth century, this project attempts to present new findings, advance future research, and build a dynamic research team. …… |
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